Question:
In adults exposed to traumatic events how effective are pharmacological interventions compared to a placebo for the prevention of post-traumatic stress disorder (PTSD)?
Answer:
One, well conducted Cochrane systematic review found some very
limited evidence that hydrocortisone may be effective in preventing
the development of post-traumatic stress disorder in adults exposed
to various traumatic experiences. Evidence was derived from four
small randomised controlled trials with a total of 165 participants
and some methodological weaknesses.
As noted by the review authors, further research is needed to
adequately assess the efficacy of hydrocortisone and other
pharmacotherapies in preventing Further research is therefore
needed to adequately assess the efficacy of various
pharmacotherapies in preventing PTSD.
To view the full summary, click the Download Document
link to the right.
To view the Cochrane review, click the Related Document
link, below.
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