For adults with Autism, what are the most effective pharmacological interventions for reducing repetitive behaviours?
Plain Language Summary
A small amount of research evidence found that medication can
help in reducing repetitive behaviours in adults with autism.
However more research is needed to find out how effective
medication is for the problem of repetitive behaviours.
Clinical and research implications
There is a lack of reliable evidence about the effectiveness of
pharmacological interventions for reducing repetitive behaviours in
adults with Autism. Two small RCTs (30 and 37 participants)
compared fluoxetine or fluvoxamine with placebo and both found that
12 weeks of pharmacological treatment significantly reduced
repetitive behaviours compared with placebo. However both were of
moderate quality and neither had another pharmacological treatment
as the comparator. Further research is needed, with larger sample
sizes and longer follow-up periods which compares different
pharmacological agents with each other, and not just to
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