For adults with learning disabilities and/or Autism, how effective is Naltrexone compared with any other or no intervention in reducing self-injurious behaviour?
We don't know for sure how effective
Naltrexone is in reducing self-harm behaviour in adults with
learning disabilities and/or autism, as there is very little high
quality or current research out there to give us a clear answer.
More rigorous research need to be conducted to give us a better
Evidence from one systematic review (27 mostly single case
studies) suggested that short-term naltrexone treatment could
reduce self-injurious behaviour in children and adults with severe
and profound cognitive impairment, including autism. Further
research should report outcomes for individual participants, use a
common set of outcome measures, and explore the relationship
between behavioural and biological markers as predictors of
response to treatment.
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