Question: In adults with dementia, how effective are vitamins, minerals and food stuffs, compared to any other intervention/treatment as usual, for slowing the progression of dementia, or for improving dementia-related symptoms?

Answer:

Overall, the available evidence suggested that neither vitamin E, vitamin B (single or combination interventions), or either of the multi-vitamin supplements assessed had any significant effect on the clinical outcomes of patients with mild to moderate AD. There was some, inconsistent evidence to suggest that omega 3 supplementation, particularly in combination with lipoic acid, may have some small positive effects on measures of cognitive function and activities of daily living; the potential effects of omega 3 supplementation may warrant further research.

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BEST Question 408.pdf

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