Question: In older adults (aged 75+) with either closed-angle glaucoma or at risk of closed-angle glaucoma, what is the association between taking antidepressant medication and either worsening or getting closed-angle glaucoma?

Answer:

No relevant systematic reviews, randomised controlled trials, or cohort/case control studies were found to answer this question. However, there have been several case studies and literature reviews suggesting an association between antidepressant use and closed-angle glaucoma. Therefore, this is a clinically relevant topic and further research is needed.

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