Weak evidence, from two randomised
controlled trials included in a systematic review and one
additional small randomised controlled trial, suggests that low
dose anti-psychotic medication may be at least as effective as
standard dose for treating people with first episode psychosis and
that lower doses are associated with fewer extrapyramidal symptoms.
The limited available evidence was for two specific drugs only,
risperidone and haloperidol. Further studies are needed to confirm
these effects and to explore the effectiveness of low doses of
other antipsychotic medications.
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