Question: What is the most effective intervention for reducing/preventing psychotic symptoms and improving social functioning in people at risk of developing first episode psychosis


There is some very limited evidence, from one generally well conducted systematic review, that cognitive behavioural therapy (CBT), integrated psychotherapy, pharmacotherapy (olanzapine), and dietary supplementation (omega 3 fatty acids) may be associated with reduced rates of transition to psychosis. However, as noted by the review authors, data were sparse and of limited quality; most comparisons were reported by a single study and analyses frequently included only those participants who completed the study.

Further research is needed to adequately assess the effectiveness of interventions for the treatment of people at high risk of psychosis.

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